Cancer (medical term: malignant neoplasm) is a class of diseases in which a cell, or a group of cells display uncontrolled growth (division beyond the normal limits), invasion (intrusion on and destruction of adjacent tissues), and sometimes metastasis (spread to other locations in the body via lymph or blood). These three malignant properties of cancers differentiate them from benign tumors, which are self-limited, and do not invade or metastasize. Most cancers form a tumor but some, like leukemia, do not. The branch of medicine concerned with the study, diagnosis, treatment, and prevention of cancer is oncology.

Cancer affects people at all ages with the risk for most types increasing with age.It caused about 13% of all human deaths in 2007 (7.6 million). Cancers are primarily an environmental disease with 90-95% of cases due to lifestyle and environmental factors and 5-10% due to genetics. Common environmental factors leading to cancer death include: tobacco (25-30%), diet and obesity (30-35%), infections (15-20%), radiation, stress, physical activity, environmental pollutants. These environmental factors cause abnormalities in the genetic material of cells.

Genetic abnormalities found in cancer typically affect two general classes of genes. Cancer-promoting oncogenes are typically activated in cancer cells, giving those cells new properties, such as hyperactive growth and division, protection against programmed cell death, loss of respect for normal tissue boundaries, and the ability to become established in diverse tissue environments. Tumor suppressor genes are then inactivated in cancer cells, resulting in the loss of normal functions in those cells, such as accurate DNA replication, control over the cell cycle, orientation and adhesion within tissues, and interaction with protective cells of the immune system.

Definitive diagnosis requires the histologic examination of a biopsy specimen, although the initial indication of malignancy can be symptomatic or radiographic imaging abnormalities. Most cancers can be treated and some forced into remission, depending on the specific type, location, and stage. Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy. As research develops, treatments are becoming more specific for different varieties of cancer. There has been significant progress in the development of targeted therapy drugs that act specifically on detectable molecular abnormalities in certain tumors, and which minimize damage to normal cells. The prognosis of cancer patients is most influenced by the type of cancer, as well as the stage, or extent of the disease. In addition, histologic grading and the presence of specific molecular markers can also be useful in establishing prognosis, as well as in determining individual treatments.

Articles About Cancer

Chuck Zito Apologises For Offensive Comment On Christy Mack Beating

By IBTimes AU

The actor issued his apology following criticisms he received from social media haters posted on his Twitter account. (6:26 pm)

MORE TOPICS: TWITTER, NEW YORK

Nutritionists warn that people in the Pacific are at risk of obesity on a Western diet
Fight Against Diabetes and Obesity: Daily Berry Intake to the Rescue

By IBTimes AU

According to The Australian, to tackle obesity-linked diabetes and metabolic syndrome, a handful of rasberries or a cup of blueberry juice should be taken daily. (4:27 pm)

MORE TOPICS: AUSTRALIA

Skin cancer
Cancer Cure: Botox May Help in Treatment of Gastric Cancer

By IBTimes AU

A study published in Science Translational Medicine, botox injections can prevent the development of gastric cancers. (1:16 pm)

MORE TOPICS: NEW YORK

Colgate toothpaste
Colgate Total: The Only Absolutely Safe Toothpaste Approved by FDA That Treats Gingivitis and Plaque and Doesn't Cause Cancer

By IBTimes AU

A certain chemical in Colgate Total that causes cancer is neither based on facts nor science. (12:34 pm)

MORE TOPICS: DENTAL

A man smokes marijuana during a gathering to welcome back marijuana advocate Marc Emery in Windsor, Ontario
Medicinal or Otherwise, Canadian Doctors Oppose Marijuana Smoking

By IBTimes AU

Even if their group has denied to give their participation to a government campaign, doctors in Canada remain against smoking marijuana, be it for medicinal purposes or not. (12:22 pm)

Shoes Using for Running
Top Reasons of a Blind Patriarch Runs 11,000 Miles

By IBTimes AU (No Google news)

David Kuhn is a retired patriarch running around the US. His mission is not only support his granddaughter but for all suffering with the cystic fibrosis (10:50 am)

A reggae fan looks at photographs of Bob Marley
Bob Marley Died Due to a Rare Skin Cancer, Scientists Learn More About The Disease

By IBTimes AU

Singer-songwriter and musician, Bob Marley's death was caused due to a rare type of skin cancer called Acral melanomas. (Aug 21)

HIV Cure: Shock-and-Kill Method Unlocks 'No Remission' Possibility for Future Treatments

By IBTimes AU

New study with 'shock-and-kill' was published in Cell journal that can flush out viral reservoirs in infected cells and later killed by boosted immune system leading to the possibility of no remission. (Aug 21)

MORE TOPICS: INFECTION

A Toddler Relishing  Bottle Of Milk
Camel Milk Holds Answer for Diabetes, Autism, Lactose Intolerance, Allergies

By IBTimes AU

Camel milk with extreme high in iron, vitamin, protein and calcium, might cure diabetes, autism and few types of allergies. It is easily digestible for those who are lactose intolerance. (Aug 21)

MORE TOPICS: AUTISM, AUSTRALIA, BREAST CANCER

David Cameron
British PM David Cameron Cuts Short Summer Holiday to Lead Hunt for Foley Beheader; Abbott Calls Decapitation ‘Pure Evil’

By IBTimes AU

British Prime Minister David Cameron was on a summer holiday when news of the beheading of American journalist James Foley sparked an international search for the man with a British accent who decapitated the newsman. Mr Cameron cut short his vacation and lead the hunt for the jihadist. (Aug 21)

MORE TOPICS: BARACK OBAMA, IRAQ, TONY ABBOTT

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