Two Drug Combination Therapy can Assist in Weight Loss: Study
By Smitha Nambiar | August 19, 2014 9:46 AM EST
A two drug combination of phentermine and topiramate can help overweight people lose weight and curb obesity, revealed a study conducted by researchers at the Austin Hospital in Melbourne, Australia.
Global 2000 has come out with its list of top 2000 companies of which many pharmaceuticals are part of.
According to the study published in the Medical Journal of Australia, a combination diet pill of phentermine (appetite suppressant) and topiramate (epilepsy drug) can help people lose weight. However, the side-effects are so severe that very people would opt for it. Heart palpitations, burning or prickling skin sensations, dry mouth and tingling, insomnia and depression are the most common side-effects of these two drugs.
As part of the study, the researchers at the Austin Hospital in Melbourne tested the drug on 103 patients who were given the combination therapy after completion of a very low calorie diet to start their weight loss program. They were then asked to be on a diet meant to maintain their weight while they continued taking the drugs.
While forty-one out of 61 people taking the drug gave up because of side effects, it was found that the average weight, for all those who completed the 22 month trial, fell by 6.7kg. This was apart from the initial mean weight loss of 16 Kgs during the early low calorie diet.
According to Professor Joseph Proietto, lead researcher, the two combination drug therapy cannot be tolerated by all, but is effective in helping people maintain their weight after weight loss. "The purpose of our paper was to describe our experience with using the combination at some maximal doses to help people maintain weight after they've lost it," said Proietto.
The drug combination of phentermine and topiramate has not yet been approved by the Therapeutic Goods Administration for weight loss in Australia. However, it has been approved by the US Food and Drug Administration. Since both the drugs are available in Australia, the GPs can prescribe these pills to their patients as "off label" fashion.
To contact the editor, e-mail:
Most Popular Slideshows
- Still The World Champions: Team USA Overpowers Serbia, 129-92 To Win 2014 FIBA World Cup [PHOTOS]
- Pope Francis: World War III Has Started On Piecemeal
- After Win Over Maidana, Mayweather Says He Is Prepared To Negotiate A Fight With Pacquiao
- From Fat To Fit: Celebrities Who Were Overweight Before They Became The Beauties That They Are
Join the Conversation
- Alien Mystery: The Most Famous Unexplained Alien Abduction Cases (Watch Video)
- University of Waterloo U Study Recommends Best Sex Positions To Ease Back Pain During Lovemaking
- Aurora Borealis Paints A Beautiful Picture On The Northern Skies [Watch Video]
- West Seattle Man Accuses Stranger Obese Woman Of Rape While He Was Asleep
- Lady Gaga Wants David Bowie To Perform With Her In Space
- Samsung Attacks iPhone 6 Plus Through New Galaxy Note 4 Commercial: Apple Claims Imitating Galaxy Note Phablets
- Pregnant Kate Middleton May Call Off Malta Trip Due To Sickness: Royal Couple Will Move To Anmer Hall Residence
- HTC ‘Double Exposure’ Event On October 8 Could Unveil HTC Eye With 5.2-inch FHD Display
- Apple iOS 8 Can Trump Google Android 5.0 L Upon September 17 Release
- Ukraine Crisis: Poland Denies Supplying Weapons To Kiev
- Twitter Photo Of British Medical Muslima Student Holding Severed Head
- Google Nexus 8 Release Date Countdown Begins Oct 8: 8 Killer Specs and Features to Expect