Rotten Eggs, Flatulence Hold Cure for Stroke, Diabetes, Dementia
By Smitha Nambiar | July 11, 2014 3:30 PM EST
Rotten Eggs and flatulence have hydrogen sulfide, which when used in the right dosage, can help in the treatment and cure of diabetes, arthritis, heart failure, dementia and ageing, says scientists at the University of Exeter. The findings of the study were published in the journal Medicinal Chemistry Communications.
Eduardo Castaneda, 45, chef and owner of La Guayaba Verde restaurant grabs an egg as he prepares dishes at the restaurant's kitchen in Caracas January 27, 2014.
Few scientists at the University of Exeter have developed a new compound - AP39, using hydrogen sulfide, present in rotten eggs and flatulence. The compound, when delivered in very small amounts to the right places inside the cells, can offer health benefits in a range of diseases such as diabetes, arthritis, heart failure, dementia and aging.
AP39 protects mitochondria, also termed as the "powerhouse" of cells. The mitochondria drives energy production in blood vessel cells. They determine the life or death of the cells and regulate inflammation. By preventing or reversing mitochondrial damage, various conditions can be treated.
Professor Matt Whiteman of Exeter Medical School, said, "When cells become stressed by disease, they draw in enzymes to generate minute quantities of hydrogen sulfide. This keeps the mitochondria ticking over and allows cells to live," He further added, "If this doesn't happen, the cells die and lose the ability to regulate survival and control inflammation. We have exploited this natural process by making a compound, called AP39, which slowly delivers very small amounts of this gas specifically to the mitochondria. Our results indicate that if stressed cells are treated with AP39, mitochondria are protected and cells stay alive."
Speaking about the benefits of hydrogen sulfide, Dr Mark Wood, from the department of Biosciences, at the University of Exeter, said, "Although hydrogen sulfide is well known as a pungent, foul-smelling gas in rotten eggs and flatulence, it is naturally produced in the body and could in fact be a healthcare hero with significant implications for future therapies for a variety of diseases." The pre-clinical results of the research are promising, and hence both Wood and Whiteman are working towards advancing the research, so that it can be tested in humans.
To contact the editor, e-mail:
Most Popular Slideshows
- Real Life ‘Frozen’: Snow Overwhelms The US, Kills 7; More To Come (Pictures)
- Angelina Jolie, Brad Pitt in Sydney for ‘Unbroken’ Red Carpet Premiere [PHOTOS]
- ‘The Walking Dead’ Season 5, Episode 8 Spoilers: Daryl Dixon Is Set To Burn The Place Down in ‘Coda’
- G20 Summit Awkward Moments: Putin Yawns, Mystery Bubbles Appear, F18 Drama Ensues
Join the Conversation
- Mars Unusual Feature: Alien Skull Buried In Martian Sand
- Seals In Antarctica Are Sexually Assaulting King Penguins
- Accidental Electrocution Makes 12-Year-Old Russian Boy ‘Magnetic’ Similar To X-Men Character
- Kid Discovers 100-million-year-old Marine Reptile Fossil
- Stephen Hawking's Facebook Posts Tell You How The Cosmologist Reacts To 'Theory Of Everything' And 'Interstellar'
- Walmart Early Price Matching Special Event On Nov. 21, 2014 Matches Its Competitors' Black Friday 2014 Prices And Includes Exclusive Deals For Samsung LED HDTVs And iPad Air 2 [WATCH VIDEO]
- US Plane Flying Over Russian Skies Spotted; Vladimir Putin Ready For 'Practical Cooperation' With US
- Alleged 'Microsoft Lumia 1030' Front Panel Leaked With Capacitive Buttons; 'Xbox One' Owners To Get Free Goodies On Anniversary
- Nexus 6 Release Date And Price Under AT&T, T-Mobile And Sprint Listed
- Walmart Pre-Black Friday 2014 Sale On Nov. 21, 2014 Includes Discounts On The 'NBA 2K15' For PS4 And The 'Skylanders Trap Team’ Starter Kit [WATCH VIDEO]
- Black Friday 2014 Sale: Top Deals On Game Consoles Xbox One, PS4, Nintendo Wii U And More
- Cold War 2: Russia, China And North Korea’s Blacklisted Company Fortify Alliance -- Reports