Post-Chemo Child Rearing May Be More Possible With New Drug, Study Reports
By Silvana Peters | June 4, 2014 2:26 PM EST
One of chemotherapy's major side effects includes infertility in both men and women of child-bearing age. This is trying and very difficult for individuals who want to be able to have children after undergoing treatment. Good news is that a new breast cancer drug may be able to prevent women from becoming infertile due to cancer treatment.
The drug, goserelin, suppresses the ovaries from premature ovarian failure during cancer treatment and seen preserve future fertility. It shuts the ovaries down protecting them from premature menopause caused by the chemotherapy.
The study was presented at the annual meeting of American Society of Clinical Oncology (ASCO) in Chicago and involved 257 women, all under the age of 50 with breast cancer whose growth was not fueled by estrogen, writes Voice of America. Findings of the study show that those who received AstraZeneca PLC's drug goserelin along with chemotherapy were 64 percent less likely to develop premature menopause than women who had chemotherapy alone and go on to have successful pregnancies.
These findings were described as "really exciting" by the study's leader, Dr. Halle Moore of the Cleveland Clinic. Fox News quotes her as describing the drug as a ""temporary menopause to prevent permanent menopause."
This may very well become a viable option that can help countless women return to their normal lives after surviving cancer. It will also encourage patients to consider more treatment options without worrying about their ability to have children in the future.
Goserelin was given monthly through a shot to half of the women. The drug lowers the body's estrogen levels effectively but temporarily resting the ovaries with side effects that include common menopause symptoms like hot flashes and vaginal dryness, notes the AP.
Eight percent of the goserelin patients become menopausal afterwards, much lower than the 22 percent who were not given the drug and 22 became pregnant compared to 12 without the drug, reports the Guardian.
"This has implications far beyond breast cancer," citing it may be an option for younger women with other types of tumors and cancers, quoted Fox News of Dr. Clifford Hudis, breast cancer chief at Memorial Sloan Kettering Cancer Center in New York City.
However, the study has only included women with hormone-receptor-negative cancer. While it is unclear how goserelin protects the ovaries, it maybe because it renders them less active during chemo and preserves them when the therapy is over.
To contact the editor, e-mail:
Most Popular Slideshows
- Flight MH17 Attack: Russians Claim 'Putin A Terrorist,' Memorial at Dutch Embassy Overflows [PHOTOS]
- Typhoon Rammasun Claims 18 Lives in China, Incurs $4.32B Losses (PHOTOS)
- Ellen DeGeneres Caught Cheating with Mutual Friend Before Portia de Rossi’s Rehab – Reports [PHOTOS]
- Selena Gomez Turns 22 Today, Celebrates Early without Justin Bieber: Top 12 Interesting Facts About the Singer [SEE PHOTOS]
Join the Conversation
- California Fruits Recalled in USA and Canada for Possible Listeria Contamination
- Malaysian Airlines Flight 17: Air Carrier Losing $1.6 Million/Day; Crisis Management Experts Suggest Hiring Risk Expert as CEO
- The IBM and Apple Merger: Will it Spell Trouble to Rival Companies
- KFC & McDonald’s Accused of Serving ‘Expired’ Meat to Customers
- CBA, NAB, Westpac in Fixed Rate War Offering Below 5% Interest
- Samsung Galaxy Note 4 Apps Leak Online, Five Fresh Features to Expect from the Android Smartphone
- Moto 360 Price Speculations, Key Features, Strategic Release Date, Design: A Watch That is More Than Just Time
- Windows Phone 8.1 Update Rollout: 20 Nokia Lumia Phones Eligible and 13 New Features to be Added
- Google Nexus 8 Release Date Soon Along with 2 More HTC Android Tablets – Reports
- Three New Moto G Successors Spotted in FCC Document Dubbed Moto G2, Moto M and More --Reports
- iPad Air 2 Release Date Will Skip IGZO Panel; To Rollout with Super-Slim iPad Mini Air
- Upcoming iPad Mini 3 Could be 30% Thinner and Likely be Called iPad Mini Air; Apple Q3 Results Show 9% Decrease in iPad Sales