The BBC Television centre has closed its doors for the final time after almost 45 years of bulletins.

Mishal Husain signed off the last ever news bulletin from the west London studios, marking the end of an era.

The iconic building, which has housed a number of shows including Blue Peter, Doctor Who and Strictly Come Dancing, opened in 1960 and the news first went out from the site in 1969.

During its four decades on air, news bulletins broadcast on BBC One have attracted audiences of up to 10 million people a day.

The entire BBC news operation has moved to Broadcasting House in central London.

Staff working on Newsnight, World TV, the news website and the BBC Red Button news pages, as well as those on radio news other than BBC Radio 5 live have already relocated to their new home in Salford.

Television Centre, which was sold for £200m in 2012, will be redeveloped into hotels, flats, a cinema and office space in 2014.

IBtimes UK has a look at defining moments captured at the BBC Television Centre.

The BBC TV Centre was opened in 1960 and the news first went out from the site in 1969.

Doctor Who is one of the greatest British exports. Here Tom Baker, who took on the role as a new Doctor Who in 1974, poses in the BBC TV Centre car park surrounded by Daleks.

Strictly Come Dancing has often beaten ITV's X factor in the ratings war

Prince Charles recorded his commentary for the pre-recorded part of his Silver Jubilee Appeal to be broadcast live on television from his country home at Chevening in Kent.

Children in Need, one of television’s biggest annual fundraising nights, was broadcast live from the television centre.

The Graham Norton Show, which has played host to stars including Rihanna and Jude Law, was originally shown on BBC Two from February 2007 to May 2009 until it moved to BBC One from October 2009.

Mishal Husain was given the honour of signing off the last TV network news bulletin from Television Centre.